Forschung verläuft nie gradlinig. Man startet mit einer These und versucht, diese im Labor oder der Klinik zu bestätigen.
THOMAS MEIER, GRÜNDER MYOCONTRACT (HEUTE SANTHERA PHARMACEUTICALS)
Transcriptional and cellular maturation of the chick spinal cord in the context of distinct neuromuscular circuits.
Sacher F, Berki B, Fages A, Gavrilov L, Klar A, Luxey M, Tschopp P.
iScience. 2026 Mar 3;29(4):115196.
03 März 2026
Identification of new interactors of eIF3f by endogenous proximity-dependent biotin labelling in human muscle cells.
Tintignac L, Mittal N, Alam S, Ataman M, Ertuna YI, Bock T, Erne B, Zavolan M, Sinnreich M.
Sci Rep. 2025 Dec 21;16(1):2812.
24 Februar 2026
Inflammation drives TGFβ1 activation via the αvβ6 integrin-mechanotransduction pathway in human skin.
Jiang X, Sellami S, Kessler J, Bachmann M, Noulet F, Russo B, Brembilla NC, Kaya G, Ivanov AI, Shutova MS, Wehrle-Haller B, Boehncke WH.
iScience,…
17 Februar 2026
Dual AAV gene therapy using laminin-linking proteins ameliorates muscle and nerve defects in LAMA2-related muscular dystrophy.
Reinhard JR, Lin S, Maino E, Ham DJ, Rüegg MA.
Mol Ther. 2026 Feb 2:S1525-0016(26)00084-5. Online ahead of print.
10 Februar 2026
Intracellular autofluorescence enables the isolation of viable, functional human muscle reserve cells with distinct Pax7 levels and stem cell states.
Bouche A, Michel D, Castets P, Hannouche D, Laumonier T.
Stem Cell Res Ther. 2025 Dec 1;17(1):12.
09 Januar 2026
Microvascular Health as a Key Determinant of Organismal Aging
Cenciarini M, Uccelli A, Mangili F, Grunewald M, Bersini S.
Adv Sci (Weinh). 2025 Dec;12(47):e08659. doi: 10.1002/advs.202508659. Epub 2025 Nov 5.
05 November 2025
Massive reduction of RyR1 in muscle spindles of mice carrying recessive Ryr1 mutations alters proprioception and causes scoliosis.
Ruiz A, Benucci S, Meier H, Schultz G, Buczak K, Handschin C, Pena RCG, Treves S, Zorzato F. J Physiol. 2025 Oct 15.
15 Oktober 2025
An updated inventory of genes essential for oxidative phosphorylation identifies a mitochondrial origin in familial Ménière’s disease
Marcell Harhai, Mads M. Foged,Christine Zarges, Juan C. Landoni, Sylvain Chollet, Michele Simonelli, Emeline Recazens, Miriam Lisci, Nora Laban,…
28 Juli 2025
5-aza-2-deoxycytidine improves skeletal muscle function in a mouse model for recessive RYR1-related congenital myopathy.
Ruiz A, Noreen F, Meier H, Buczak K, Zorzato F, Treves S.
Hum Mol Genet. 2025 Apr 17;34(9):790-805.
28 April 2025
Recent advances in the clinical spectrum and pathomechanisms associated with X-linked myopathy with excessive autophagy and other VMA21-related disorders.
Cocchiararo I, Castets P.
J Neuromuscul Dis. 2025 Mar 4:22143602251314767.
04 März 2025