A large animal model of Spinal Muscular Atrophy and correction of phenotype.

Duque SI, Arnold WD, Odermatt P, Li X, Porensky PN, Schmelzer L, Meyer K, Kolb SJ, Schümperli D, Kaspar BK, Burghes AH. Ann Neurol. 2014 Dec 16.

16 décembre 2014

Raptor ablation in skeletal muscle decreases Cav1.1 expression and affects the function of the excitation-contraction coupling supramolecular complex.

Lopez RJ, Mosca B, Treves S, Maj M, Bergamelli L, Calderon JC, Bentzinger CF, Romanino K, Hall MN, Rüegg MA, Delbono O, Caputo C, Zorzato F. Biochem J. 2014 Nov 28.

28 novembre 2014

ENMC Workshop report: SMA outcomes and clinical trial readiness

Richard Finkel, Enrico Bertini, Francesco Muntoni and Eugenio Mercuri 7-9 November 2014, Heemsklerk, The Netherland

18 novembre 2014

Inositol 1,4,5 trisphosphate receptor 1 is a key player of human myoblast differentiation.

Antigny F, Konig S, Bernheim L, Frieden M. Cell Calcium. 2014 Nov 4;56(6):513-521.

04 novembre 2014

The FgfrL1 receptor is required for development of slow muscle fibers.

Amann R, Wyder S, Slavotinek AM, Trueb B. Dev Biol. 2014 Oct 15;394(2):228-41.

15 octobre 2014

The craniosacral progression of muscle development influences the emergence of neuromuscular junction alterations in a severe murine model for spinal muscular atrophy.

Voigt T, Neve A, Schümperli D. Neuropathol Appl Neurobiol. 2014 Jun;40(4):416-34

19 septembre 2014

A PiggyBac-mediated approach for muscle gene transfer or cell therapy.

Ley D, Van Zwieten R, Puttini S, Iyer P, Cochard A, Mermod N. Stem Cell Res. 2014 Sep 8;13(3PA):390-403.

08 septembre 2014

The coactivator PGC-1α regulates skeletal muscle oxidative metabolism independently of the nuclear receptor PPARβ/δ in sedentary mice fed a regular chow diet.

Pérez-Schindler J, Svensson K, Vargas-Fernández E, Santos G, Wahli W, Handschin C. Diabetologia. 2014 Aug 13.

25 août 2014

Santhera Repositions Omigapil in Congenital Muscular Dystrophy and Initiates Clinical Development Program with Public-Private Partners

17 juillet 2014

Assessing dystrophies and other muscle diseases at the nanometer scale by atomic force microscopy.

van Zwieten RW, Puttini S, Lekka M, Witz G, Gicquel-Zouida E, Richard I, Lobrinus JA, Chevalley F, Brune H, Dietler G, Kulik A, Kuntzer T, Mermod N. Nanomedicine...

12 juin 2014