Grant opportunity

The SMA Europe call for operating grants and postdoctoral fellowships is now open.

Deadline: 29 April 2024


18th International Conference on Neuromuscular Diseases

Perth, 25-29 October 2024

This edition will be dedicated to the rapidly evolving area of precision medicine and highlight the recent successes in this field and the great potential for the development of new therapies for other currently incurable neuromuscular diseases.

Late breaking abstracts submission opens on June 3rd


Grant opportunity

The RYR-1 Foundation is Accepting Letters of Intent (LOIs) for the Individual Investigator Research Grant Awards.

Deadline: May 18, 2024


ENMC Workshop report

The lay report on the workshop "Seronegative MG: An update paradigm for diagnosis and management", held in The Netherlands on 9-11 February 2024, is now available in 8 languages on the ENMC website. The full report will be published in the next 6 months on Neuromuscular Disorders.

Workshop report and participants list


Myology 2024

Paris, 22-25 April 2024

This conference offers a comprehensive overview of the latest breakthroughs in muscle science, with a particular focus on disease-modifying therapies and medical advancements for neuromuscular diseases .

Registration open


New papers


A novel, patient-derived RyR1 mutation impairs muscle function and calcium homeostasis in mice.

Benucci S, Ruiz A, Franchini M, Ruggiero L, Zoppi D, Sitsapesan R, Lindsay C, Pelczar P, Pietrangelo L, Protasi F, Treves S, Zorzato F.
J Gen Physiol. 2024 Apr 1;156(4):e202313486.

01 April 2024

A solid beta-sheet structure is formed at the surface of FUS droplets during aging.

Emmanouilidis L, Bartalucci E, Kan Y, Ijavi M, Pérez ME, Afanasyev P, Boehringer D, Zehnder J, Parekh SH, Bonn M, Michaels TCT, Wiegand T, Allain FH.
Nat Chem Biol. 2024 Mar 11.

12 März 2024

Cervical and thoracic spinal cord gray matter atrophy is associated with disability in patients with amyotrophic lateral sclerosis.

Wendebourg MJ, Weigel M, Weidensteiner C, Sander L, Kesenheimer E, Naumann N, Haas T, Madoerin P, Braun N, Neuwirth C, Weber M, Jahn K, Kappos L, Granziera C, Schweikert K, Sinnreich M, Bieri O,...

11 März 2024

SNUPN deficiency causes a recessive muscular dystrophy due to RNA mis-splicing and ECM dysregulation.

Nashabat M, Nabavizadeh N, Saraçoğlu HP, Sarıbaş B, et al.
Nat Commun. 2024 Feb 27;15(1):1758.

27 Februar 2024

A model of human neural networks reveals NPTX2 pathology in ALS and FTLD.

Hruska-Plochan M, Wiersma VI, Betz KM, Mallona I, Ronchi S, Maniecka Z, Hock EM, Tantardini E, Laferriere F, Sahadevan S, Hoop V, Delvendahl I, Pérez-Berlanga M, Gatta B, Panatta M, van der Bourg A,...

14 Februar 2024

Direct reprogramming of non-limb fibroblasts to cells with properties of limb progenitors.

Atsuta Y, Lee C, Rodrigues AR, Colle C, Tomizawa RR, Lujan EG, Tschopp P, Galan L, Zhu M, Gorham JM, Vannier JP, Seidman CE, Seidman JG, Ros MA, Pourquié O, Tabin CJ.
Dev Cell. 2024 Feb...

05 Februar 2024

Autoreactive T cells target peripheral nerves in Guillain-Barré syndrome.

Súkeníková L, Mallone A, Schreiner B, Ripellino P, Nilsson J, Stoffel M, Ulbrich SE, Sallusto F, Latorre D.
Nature. 2024 Jan 17. doi: 10.1038/s41586-023-06916-6.

17 Januar 2024

Native collagen VI delays muscle stem cell early differentiation.

Metti S, Ros FD, Toniato G, Cescon M, Bonaldo P.
J Cell Sci. 2024 Jan 15:jcs.261419.

15 Januar 2024

The ER stress sensor IRE1 interacts with STIM1 to promote store-operated calcium entry, T cell activation, and muscular differentiation.

Carreras-Sureda A, Zhang X, Laubry L, Brunetti J, Koenig S, Wang X, Castelbou C, Hetz C, Liu Y, Frieden M, Demaurex N.
Cell Rep. 2023 Dec 26;42(12):113540.

26 Dezember 2023

Respiratory function in a large cohort of treatment-naïve adult spinal muscular atrophy patients: a cross-sectional study.

Vicino A, Bello L, Bonanno S, Govoni A, Cerri F, Ferraro M, Capece G, Gadaleta G, Meneri M, Vacchiano V, Ricci G, D'Errico E, Tramacere I, Banfi P, Bortolani S, Zanin R, Maioli MA, Silvestrini M,...

22 Dezember 2023